Johnson & Johnson’s prostate cancer drug shrinks tumours in early-stage trial

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Newsonline

Joined: Aug 2026

Johnson & Johnson on Saturday said its experimental once-daily oral prostate cancer drug caused tumours to disappear or shrink in an early-stage trial.

J&J had gained access to the drug through its $3.05bn (R50.6bn) deal to buy Halda Therapeutics last year.

The company was testing JNJ-6143 in patients with advanced prostate cancer who had received multiple treatments.

Its novel approach selectively kills cancer cells by interfering with a protein they need to survive.

It adds a new mechanism of action to J&J’s prostate cancer portfolio,

a Johnson & Johnson spokesperson said.

Common side effects were nausea and elevated cholesterol and triglyceride levels.

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